Search on: BETA-ISOPROPYLMALATE DEHYDROGENASE 
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Descriptor English:   3-Isopropylmalate Dehydrogenase 
Descriptor Spanish:   3-Isopropilmalato Deshidrogenasa 
Descriptor Portuguese:   3-Isopropilmalato Desidrogenase 
Synonyms English:   beta-IPM Dehydrogenase
beta-Isopropylmalate Dehydrogenase
3 Isopropylmalate Dehydrogenase
Dehydrogenase, 3-Isopropylmalate
Dehydrogenase, beta-IPM
Dehydrogenase, beta-Isopropylmalate
beta IPM Dehydrogenase
beta Isopropylmalate Dehydrogenase  
Tree Number:   D08.811.682.047.820.193
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use DICARBOXYLIC ACIDS 1970-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50598 
Unique Identifier:   D050539 

Occurrence in VHL:
 

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